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What is zituvimet XR used for?

ZITUVIMET XR is a prescription medicine that contains 2 prescription diabetes medicines, sitagliptin and extendedrelease metformin hydrochloride. ZITUVIMET XR is used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. ZITUVIMET XR is not for people with type 1 diabetes. ...

How do I take zituvimet XR?

Take ZITUVIMET XR orally once daily with a meal. Patients taking two ZITUVIMET XR tablets should take the two tablets together once daily. Individualize the dosage of ZITUVIMET XR on the basis of the patientâ€™s current regimen, effectiveness, and tolerability. ...

Is zituvimet XR safe for patients with diabetes mellitus?

ZITUVIMET XR is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. ZITUVIMET XR is not recommended in patients with type 1 diabetes mellitus. ZITUVIMET XR has not been studied in patients with a history of pancreatitis. ...

When should I discontinue zituvimet XR?

Discontinue ZITUVIMET XR at the time of, or prior to, an iodinated contrast imaging procedure in patients with an eGFR between 30 and 60 mL/min/1.73 m²; in patients with a history of liver disease, alcoholism, or heart failure; or in patients who will be administered intra-arterial iodinated contrast. ...

Does zituvimet XR contain FD&C?

Additionally, ZITUVIMET XR 50 mg/500 mg and 100 mg/1,000 mg tablets film-coating contain the inactive ingredient red iron oxide and 50 mg/1,000 mg and 100 mg/1,000 mg tablets film-coating contain the FD&C yellow#6 Aluminum Lake. This Medication Guide has been approved by the U.S. Food and Drug Administration. ...

Which antihyperglycemic medications are used in zituvimet XR?

Prompt hemodialysis is recommended [see WARNINGS AND PRECAUTIONS]. ZITUVIMET XR tablets for oral use contain two antihyperglycemic medications: sitagliptin and metformin hydrochloride. Sitagliptin is an orally-active inhibitor of the DPP-4 enzyme. Sitagliptin free base drug substance is used to manufacture ZITUVIMET XR. ...