Novel biomarkers for monitoring and management of …

1 day ago · Due to current challenges in the early detection, less than 40% of individuals diagnosed with hepatocellular carcinoma (HCC) are viable candidates for surgical intervention. Therefore, validating and launching of a novel precise diagnostic approach is essential for …

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6 days ago · In 2020, liver cancer accounted for 410,000 new cases and 390,000 deaths in China, representing 45.6% and 47.1% of global totals, respectively—the highest in the world …

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FAQs about Novel biomarkers for monitoring and management of … Coupon?

What are cancer biomarkers?

Cancer biomarkers provide varied information about cancer, from early detection of malignancy to decisions on treatment and subsequent monitoring. A large variety of molecular, histologic, radiographic, or physiological entities or features are among the common types of cancer biomarkers. ...

What is a diagnostic biomarker?

Evaluating variations of DNA, RNA, and protein in the plasma or tissue of cancer cells can lead to the assessment, prediction, and diagnosis of cancers. Diagnostic Biomarkers are used to detect the presence of condition interest to identify individuals with a subtype of the disease . ...

What is a genetic biomarker?

Genetic biomarkers involve analyzing DNA or RNA for mutations, deletions, or other genetic alterations that may be associated with cancer. (19,22) Examples include BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) mutations in breast and ovarian cancer, and mutations in EGFR common in lung cancer. ...

What are biomarkers used for?

Biomarkers are used to monitor the development of a disease. Before diagnosis, screening and risk assessment. During diagnosis, they can assist in the determination of staging, grading, and primary therapy selection, and after diagnosis, for monitoring therapy, additional therapy selection, or monitoring recurrent diseases [, , ]. ...

What biomarkers can be used in clinical trials?

The utilization of diverse biomarkers will become increasingly prevalent in clinical trials, especially for a wide range of illnesses. Blood-based biomarkers, such as circulating tumor DNA (ctDNA), exosomes, and microRNAs, hold immense potential. ...

What is a network biomarker?

Network biomarkers can be thought of as a continuation of module biomarkers, where the interaction from several Meta modules helps to systematically understand the aetiology and treatment of disease and encourages the development of new methods for examining genetic or epigenetic changes across the disease. ...